TMZ(Temozolomide)
S1237
CAS Number85622-93-1
Product group Chemicals
Estimated Purity...
Overview
- SupplierSelleck Chemicals
- Product NameTemozolomide (CCRG 81045) [85622-93-1]
- Delivery Days Customer9
- CAS Number85622-93-1
- CertificationResearch Use Only
- Estimated Purity...
- Scientific DescriptionTMZ(Temozolomide) is a monofunctional SN-1 alkylating agent that can modify nitrogen atoms in the DNA ring and the extracyclic oxygen group, chemically converted to MTIC and degrades to methyldiazonium cation, which transfers methyl groups to DNA at physiologic pH. A DNA damage inducer in L-1210 and L-1210/BCNU cells. Temozolomide induces apoptosis and exhibits antitumor activity.
- UNSPSC12352200