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Tenovin-6 (Hydrochloride) [1011301-29-3]

HY-15510B
MedChem Express
CAS Number1011301-29-3
Product group Chemicals
Estimated Purity98.88
Molecular Weight491.09
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tenovin-6 (Hydrochloride) [1011301-29-3]
  • Delivery Days Customer
    10
  • CAS Number
    1011301-29-3
  • Certification
    Research Use Only
  • Estimated Purity
    98.88
  • Molecular Formula
    C25H35ClN4O2S
  • Molecular Weight
    491.09
  • Scientific Description
    Tenovin-6 Hydrochloride, an analog of Tenovin-1 (HY-13423), is an activator of p53 transcriptional activity. Tenovin-6 Hydrochloride inhibits the protein deacetylase activities of purified human SIRT1, SIRT2, and SIRT3 with IC50s of 21 microM, 10 microM, and 67 microM, respectively. Tenovin-6 Hydrochloride also inhibits dihydroorotate dehydrogenase (DHODH)[1][2].
  • SMILES
    O=C(NC(NC1=CC=C(NC(CCCCN(C)C)=O)C=C1)=S)C2=CC=C(C(C)(C)C)C=C2.Cl
  • Storage Instruction
    2°C to 8°C
  • UNSPSC
    12352200