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Tenovin-6 Hydrochloride

T8480
TargetMol Chemicals
CAS Number1011301-29-3
Product group Chemicals
Molecular Weight491.09
Price on request
Packing Size
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Tenovin-6 Hydrochloride
  • Delivery Days Customer
    4
  • CAS Number
    1011301-29-3
  • Category Supplier
    Chemical
  • Chemical Name
    Tenovin-6 Hydrochloride
  • Molecular Formula
    C25H35ClN4O2S
  • Molecular Weight
    491.09
  • Scientific Description
    Tenovin-6 Hydrochloride is an SIRT1, SIRT2 and HDAC8 inhibitor(IC50s of 21 uM, 10 uM, and 67 uM for SirT1, SirT2, and SirT3, respectively), and is also a potent p53 activator .
  • Shelf life instruction
    3 years
  • SMILES
    Cl.CN(C)CCCCC(=O)NC1=CC=C(NC(=S)NC(=O)C2=CC=C(C=C2)C(C)(C)C)C=C1
  • Storage Instruction
    -20°
  • UNSPSC
    12352200

References

  • Dai W, et al. Class III-specific HDAC inhibitor Tenovin-6 induces apoptosis, suppresses migration and eliminates cancer stem cells in uveal melanoma. Sci Rep. 2016 Mar 4;6:22622.
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