Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA764560ESR1HU at dilution of 1:100
Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA764560ESR1HU at dilution of 1:100
TET2 Antibody
CSB-PA764560ESR1HU
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
TargetTET2
Overview
- SupplierCusabio
- Product NameTET2 Antibody
- Delivery Days Customer20
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID54790
- Target nameTET2
- Target descriptiontet methylcytosine dioxygenase 2
- Target synonymsIMD75; KIAA1546; MDS; methylcytosine dioxygenase TET2; probable methylcytosine dioxygenase TET2; ten-eleven translocation 2; tet oncogene family member 2
- HostRabbit
- IsotypeIgG
- Protein IDQ6N021
- Protein NameMethylcytosine dioxygenase TET2
- Scientific DescriptionDioxygenase that catalyzes the conversion of the modified genomic base 5-methylcytosine (5mC) into 5-hydroxymethylcytosine (5hmC) and plays a key role in active DNA demethylation. Has a preference for 5-hydroxymethylcytosine in CpG motifs. Also mediates subsequent conversion of 5hmC into 5-formylcytosine (5fC), and conversion of 5fC to 5-carboxylcytosine (5caC). Conversion of 5mC into 5hmC, 5fC and 5caC probably constitutes the first step in cytosine demethylation. Methylation at the C5 position of cytosine bases is an epigenetic modification of the mammalian genome which plays an important role in transcriptional regulation. In addition to its role in DNA demethylation, also involved in the recruitment of the O-GlcNAc transferase OGT to CpG-rich transcription start sites of active genes, thereby promoting histone H2B GlcNAcylation by OGT.
- Storage Instruction-20°C or -80°C
- UNSPSC12352203
Related products
Product group Antibodies
References
Goat anti-TET2EB09642
ApplicationsFlow Cytometry, ELISA, ImmunoHistoChemistry
TargetTET2
- SizePrice
Product group Antibodies
TET2 antibody [N2], N-termGTX124204
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry
TargetTET2
- SizePrice
Product group Antibodies
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetTET2
- SizePrice
Product group Antibodies
Anti-TET2 AntibodyAMAB91439
ApplicationsWestern Blot, ImmunoCytoChemistry, ImmunoHistoChemistry
TargetTET2
- SizePrice
Product group Antibodies
Anti-TET2 Antibody144-63666
ApplicationsWestern Blot, ImmunoHistoChemistry
TargetTET2
- SizePrice
Product group Antibodies
Anti-TET2 AntibodyA00191-3
ApplicationsImmunoPrecipitation, Western Blot, ImmunoHistoChemistry
TargetTET2
- SizePrice
Product group Antibodies
TET2 Polyclonal AntibodyBS-9449R
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
TargetTET2
- SizePrice
