TFPI antibody [19G38]
GTX53085
Overview
- SupplierGeneTex
- Product NameTFPI antibody [19G38]
- Delivery Days Customer9
- Application Supplier NoteELISA: 1:1000 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsELISA
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID19G38
- Concentration200 ug/ml
- ConjugateUnconjugated
- Gene ID7035
- Target nameTFPI
- Target descriptiontissue factor pathway inhibitor
- Target synonymsanti-convertin; EPI; extrinsic pathway inhibitor; LACI; TFI; TFPI1; tissue factor pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
- HostMouse
- IsotypeIgG2
- Protein IDP10646
- Protein NameTissue factor pathway inhibitor
- Scientific DescriptionThis gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203