TFPI antibody, C-term

GeneTex

TFPI antibody, C-term - Overexpression Validated

9

This antibody is expected to recognize isoform a (NP_006278.1) only.

WB: 0.3-1microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

TFPI

tissue factor pathway inhibitor

anti-convertin; EPI; extrinsic pathway inhibitor; LACI; TFI; TFPI1; tissue factor pathway inhibitor; tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

Goat

IgG

Tissue factor pathway inhibitor

This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. [provided by RefSeq, Jul 2016]

Human

-20°C or -80°C,2°C to 8°C

12352203