TGF beta 2 antibody

GeneTex

TGF beta 2 antibody

9

The antibody recognizes TGF-β2 and TGF-β1.2. By immunoblotting (non-reducing conditions) and ELISA, the antibody shows less than 2% cross-reactivity with TGF-β1, TGF-β3, and TGF-β5.

WB: 0.1-0.2 microg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin, Neutralisation/Blocking

Research Use Only

Polyclonal

Unconjugated

TGFB2

transforming growth factor beta 2

BSC-1 cell growth inhibitor; cetermin; glioblastoma-derived T-cell suppressor factor; G-TSF; LDS4; polyergin; prepro-transforming growth factor beta-2; TGF-beta2; transforming growth factor beta-2 proprotein

Goat

IgG

Transforming growth factor beta-2

Transforming Growth Factor beta 2 (TGF beta 2) is a member of the TGF beta family of growth factors. The TGF beta polypeptides are multifunctional; capable of influencing cell proliferation, differentiation, and other functions in a wide range of cell types. Transformed, as well as nonneoplastic tissues, release transforming growth factors; and essentially all mammalian cells possess a specific TGF receptor. The multi-modal nature of TGF beta is seen in its ability to stimulate or inhibit cellular proliferation. In general, cells of mesenchymal origin appear to be stimulated by TGF beta whereas cells of epithelial or neuroectodermal origin are inhibited by the peptide. TGF beta 1, TGF beta 2, and TGF beta 1.2 appear to be equivalent in biological activity, although there does appear to be differences in binding to certain types of receptors. TGF beta 2 is produced by many cell types and has been found in the highest concentration in porcine platelets and mammalian bone. Latent TGF beta 2 is the prominent isoform found in body fluids such as amniotic fluid, breast milk, and the aqueous and vitreous humor of the eye.

Human, Porcine

-20°C or -80°C,2°C to 8°C

12352203