TGF beta antibody [2C5]

GeneTex

TGF beta antibody [2C5]

9

Western blotting demonstrated that this antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa.) forms of TGF beta under both non-reducing and reducing conditions respectively. This antibody recognizes both human platelet-derived and recombinan

ELISA: Use at an assay dependent dilution. WB: Use at an assay dependent dilution. This antibody reacts with the dimeric (25 kDa) and monomeric (12.5 kDa) forms of TGF beta. When used at an antibody concentration of 5-20 ng/mL, GTX18679 will allow visualization of 100 ng/lane of TGF beta Detects a band of approximately 25 and 12.5 kDa. Optimal dilutions/concentrations should be determined by the end user.

Western Blot, ELISA

Research Use Only

Monoclonal

2C5

1 mg/ml

Unconjugated

Liquid

TGFB1

transforming growth factor beta 1

CED; DPD1; IBDIMDE; LAP; latency-associated peptide; prepro-transforming growth factor beta-1; TGFB; TGFbeta; TGF-beta1; TGF-beta-1; transforming growth factor beta1; transforming growth factor beta-1 proprotein

Mouse

IgG1

TGF beta is a multifunctional peptide that controls proliferation, differentiation, and other functions in many cell types. TGF beta acts synergistically with TGFA in inducing transformation. It also acts as a negative autocrine growth factor. Dysregulation of TGF-beta activation and signaling may result in apoptosis. Many cells synthesize TGF-beta and almost all of them have specific receptors for this peptide. TGFB1, TGFB2 and TGFB3 all function through the same receptor signaling systems.

Human

-20°C or -80°C,2°C to 8°C

12352203