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ProductsBack/Thapsigargin [67526-95-8]
Chemical Structure
Chemical Structure
Chemical Structure

Thapsigargin [67526-95-8]

Research Use Only
CDX-T0284
Chemodex
CAS Number67526-95-8
DownloadDatasheet
Product group Chemicals
Estimated Purity>98%
Molecular Weight650.75
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Overview

  • Supplier
    Chemodex
  • Product Name
    Thapsigargin [67526-95-8]
  • Delivery Days Customer
    10
  • CAS Number
    67526-95-8
  • Certification
    Research Use Only
  • Estimated Purity
    >98%
  • Hazard Information
    Danger
  • Molecular Formula
    C34H50O12
  • Molecular Weight
    650.75
  • Scientific Description
    Chemical. CAS: 67526-95-8. Formula: C34H50O12. Molecular Weight: 650.75. Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM). Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells. Thapsigargin shows anti-inflammatory and anti-cancer effects. - Thapsigargin is a non-competitive, cell permeable inhibitor of calcium transport by SERCAs (IC50 values are cell type-dependent and range from ~2-80 nM). Inhibition of SERCAs leads to an increase in intracellular calcium, which has been linked to cell activation, release of histamine from mast cells, and increased proliferation of certain types of cancer cells. Thapsigargin shows anti-inflammatory and anti-cancer effects.
  • SMILES
    O=C1OC2C3=C(C)[C@@H](OC(/C(C)=C\C)=O)[C@@H](OC(CCCCCCC)=O)[C@]3([H])[C@](C)(OC(C)=O)C[C@@H](OC(CCC)=O)[C@]2(O)[C@@]1(O)C
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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