Thrombopoietin antibody [1Z3]

GeneTex

Thrombopoietin antibody [1Z3]

9

WB: 1:500 - 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Monoclonal

1Z3

500 ug/ml

Unconjugated

THPO

thrombopoietin

c-mpl ligand; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; megakaryocyte stimulating factor; MGDF; MKCSF; ML; MPL ligand; MPLLG; myeloproliferative leukemia virus oncogene ligand; prepro-thrombopoietin; THCYT1; thrombopoietin; TPO

Mouse

IgG1

Thrombopoietin

Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5 UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203