IHC-P analysis of human thyroid tissue using GTX16853 Thyroglobulin antibody [1D4].
IHC-P analysis of human thyroid tissue using GTX16853 Thyroglobulin antibody [1D4].
Thyroglobulin antibody [1D4]
GTX16853
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTG
Overview
- SupplierGeneTex
- Product NameThyroglobulin antibody [1D4]
- Delivery Days Customer9
- Application Supplier NoteIHC-P: 1:25-1:50. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1D4
- ConjugateUnconjugated
- Gene ID7038
- Target nameTG
- Target descriptionthyroglobulin
- Target synonymsAITD3; TGN; thyroglobulin
- HostMouse
- IsotypeIgG2a
- Protein IDP01266
- Protein NameThyroglobulin
- Scientific DescriptionThyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203