IHC-P analysis of human thyroid carcinoma section using GTX02721 Thyroglobulin antibody [TGB/1968R].
Thyroglobulin antibody [TGB/1968R]
GTX02721
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTG
Overview
- SupplierGeneTex
- Product NameThyroglobulin antibody [TGB/1968R]
- Delivery Days Customer9
- ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDTGB/1968R
- Concentration200 ug/ml
- ConjugateUnconjugated
- Gene ID7038
- Target nameTG
- Target descriptionthyroglobulin
- Target synonymsAITD3; TGN; thyroglobulin
- HostRabbit
- IsotypeIgG
- Scientific DescriptionThyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis. [provided by RefSeq, Nov 2009]
- ReactivityHuman
- Storage Instruction2°C to 8°C
- UNSPSC12352203