Thyroid Hormone Receptor beta (cleaved Arg327) antibody

GeneTex

Thyroid Hormone Receptor beta (cleaved Arg327) antibody

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Thyroid Hormone Receptor beta (cleaved Arg327) antibody detects endogenous levels of fragment of activated THRB resulting from cleavage adjacent to Arg327.

WB: 1:500~1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot

Research Use Only

Polyclonal

Unconjugated

THRB

thyroid hormone receptor beta

C-ERBA-2; C-ERBA-BETA; ERBA2; GRTH; NR1A2; nuclear receptor subfamily 1 group A member 2; oncogene ERBA2; PRTH; THR1; THRB1; THRB2; thyroid hormone nuclear receptor beta variant 1; thyroid hormone receptor beta; thyroid hormone receptor, beta (erythroblastic leukemia viral (v-erb-a) oncogene homolog 2, avian); TRbeta

Rabbit

IgG

Thyroid hormone receptor beta

The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008]

Human

-20°C or -80°C,2°C to 8°C

12352203