![THZ-P1-2 [2058075-45-7] THZ-P1-2 [2058075-45-7]](https://www.targetmol.com/group3/M00/36/1A/CgoaEGayN7-ESkUVAAAAAGPvARk217.png)
THZ-P1-2 [2058075-45-7]
T39459
CAS Number2058075-45-7
Product group Chemicals
Molecular Weight531.61
Overview
- SupplierTargetMol Chemicals
- Product NameTHZ-P1-2 [2058075-45-7]
- Delivery Days Customer14
- CAS Number2058075-45-7
- CertificationResearch Use Only
- Chemical NameTHZ-P1-2
- Molecular FormulaC31H29N7O2
- Molecular Weight531.61
- Scientific DescriptionTHZ-P1-2 is a selective and potent PI5P4K inhibitor with anti-leukemic activity that acts by disrupting mitochondrial homeostasis and autophagy.THZ-P1-2 induces cell death and mitochondrial damage, and can be used in the study of leukemias.
- Shelf life instruction3 years
- SMILESCN(C)C\C=C\C(=O)Nc1ccc(cc1)C(=O)Nc1cccc(Nc2cc(ncn2)-c2c[nH]c3ccccc23)c1
- Storage Instruction-20°C
- UNSPSC12352200
References
- Sivakumaren SC, Shim H, Zhang T, et al. Targeting the PI5P4K Lipid Kinase Family in Cancer Using Covalent Inhibitors. Cell Chem Biol. 2020,27(5):525-537.e6. doi: 10.1016/j.chembiol.2020.02.003Read this paper