IHC-P analysis of human breast adenocarcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
![IHC-P analysis of human colon adenocarcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1452_IHC-P_w_23061419_888.webp "IHC-P analysis of human colon adenocarcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human ovary adenocarcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1453_IHC-P_w_23061419_741.webp "IHC-P analysis of human ovary adenocarcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human kidney carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1454_IHC-P_w_23061419_530.webp "IHC-P analysis of human kidney carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human lung carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1455_IHC-P_w_23061419_115.webp "IHC-P analysis of human lung carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human pancreas carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1456_IHC-P_w_23061419_240.webp "IHC-P analysis of human pancreas carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human thyroid carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1457_IHC-P_w_23061419_853.webp "IHC-P analysis of human thyroid carcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human breast tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1458_IHC-P_w_23061419_217.webp "IHC-P analysis of human breast tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human colon tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1459_IHC-P_w_23061419_369.webp "IHC-P analysis of human colon tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
![IHC-P analysis of human kidney tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.](https://www.genetex.com/upload/website/prouct_img/normal/GTX83492/GTX83492_1460_IHC-P_w_23061419_523.webp "IHC-P analysis of human kidney tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.")
IHC-P analysis of human breast adenocarcinoma tissue using GTX83492 TIF1 gamma antibody [9D4]. Antigen retrieval : Heat-induced epitope retrieval by 10mM citrate buffer, pH6.0, 100oC for 10min.
TIF1 gamma antibody [9D4]
GTX83492
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTRIM33
Overview
- SupplierGeneTex
- Product NameTIF1 gamma antibody [9D4]
- Delivery Days Customer9
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID9D4
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID51592
- Target nameTRIM33
- Target descriptiontripartite motif containing 33
- Target synonymsE3 ubiquitin-protein ligase TRIM33; ECTO; ectodermin homolog; protein Rfg7; PTC7; RET-fused gene 7 protein; RFG7; RING-type E3 ubiquitin transferase TRIM33; TF1G; TIF1G; TIF1GAMMA; TIF1-gamma; TIFGAMMA; transcriptional intermediary factor 1 gamma
- HostMouse
- IsotypeIgG2a
- Scientific DescriptionActs as an E3 ubiquitin-protein ligase. Promotes SMAD4 ubiquitination, nuclear exclusion and degradation via the ubiquitin proteasome pathway. According to PubMed:16751102, does not promote a decrease in the level of endogenous SMAD4. May act as a transcriptional repressor. Inhibits the transcriptional response to TGF-beta/BMP signaling cascade. Plays a role in the control of cell proliferation. Its association with SMAD2 and SMAD3 stimulates erythroid differentiation of hematopoietic stem/progenitor (By similarity). Monoubiquitinates SMAD4 and acts as an inhibitor of SMAD4-dependent TGF-beta/BMP signaling cascade (Monoubiquitination of SMAD4 hampers its ability to form a stable complex with activated SMAD2/3 resulting in inhibition of TGF-beta/BMP signaling cascade).
- ReactivityHuman
- Storage Instruction2°C to 8°C,-20°C or -80°C
- UNSPSC12352203