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TIP60 antibody

GTX112197
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKAT5
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Overview

  • Supplier
    GeneTex
  • Product Name
    TIP60 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.67 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10524
  • Target name
    KAT5
  • Target description
    lysine acetyltransferase 5
  • Target synonyms
    ESA1, HTATIP, HTATIP1, NEDFASB, PLIP, TIP, TIP60, ZC2HC5, cPLA2, histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, HIV-1 Tat interactive protein, 60kDa, K(lysine) acetyltransferase 5, K-acetyltransferase 5, Tat interacting protein, 60kDa, cPLA(2)-interacting protein, cPLA2 interacting protein, histone acetyltransferase HTATIP, protein 2-hydroxyisobutyryltransferase KAT5, protein acetyltransferase KAT5, protein crotonyltransferase KAT5, protein lactyltransferase KAT5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92993
  • Protein Name
    Histone acetyltransferase KAT5
  • Scientific Description
    The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Idrissou M, Boisnier T, Sanchez A, et al. TIP60/P400/H4K12ac Plays a Role as a Heterochromatin Back-up Skeleton in Breast Cancer. Cancer Genomics Proteomics. 2020,17(6):687-694. doi: 10.21873/cgp.20223
    Read this paper
  • Bulut-Karslioglu A, Macrae TA, Oses-Prieto JA, et al. The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output. Cell Stem Cell. 2018,22(3):369-383.e8. doi: 10.1016/j.stem.2018.02.004
    Read this paper
  • Ashraf W, Bronner C, Zaayter L, et al. Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell. J Exp Clin Cancer Res. 2017,36(1):188. doi: 10.1186/s13046-017-0659-1
    Read this paper