TIP60 antibody
GTX112197
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKAT5
Overview
- SupplierGeneTex
- Product NameTIP60 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.67 mg/ml
- ConjugateUnconjugated
- Gene ID10524
- Target nameKAT5
- Target descriptionlysine acetyltransferase 5
- Target synonyms60 kDa Tat-interactive protein; cPLA(2)-interacting protein; cPLA2; cPLA2 interacting protein; ESA1; histone acetyltransferase HTATIP; histone acetyltransferase KAT5; HIV-1 Tat interactive protein, 60kDa; HTATIP; HTATIP1; K(lysine) acetyltransferase 5; K-acetyltransferase 5; NEDFASB; PLIP; Tat interacting protein, 60kDa; TIP; TIP60; ZC2HC5
- HostRabbit
- IsotypeIgG
- Protein IDQ92993
- Protein NameHistone acetyltransferase KAT5
- Scientific DescriptionThe protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- TIP60/P400/H4K12ac Plays a Role as a Heterochromatin Back-up Skeleton in Breast Cancer. Idrissou M et al., 2020 Nov-Dec, Cancer Genomics ProteomicsRead more
- The Transcriptionally Permissive Chromatin State of Embryonic Stem Cells Is Acutely Tuned to Translational Output. Bulut-Karslioglu A et al., 2018 Mar 1, Cell Stem CellRead more
- Interaction of the epigenetic integrator UHRF1 with the MYST domain of TIP60 inside the cell. Ashraf W et al., 2017 Dec 21, J Exp Clin Cancer ResRead more