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TIP60 antibody

GTX112198
GeneTex
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKAT5
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Overview

  • Supplier
    GeneTex
  • Product Name
    TIP60 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1.67 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID10524
  • Target name
    KAT5
  • Target description
    lysine acetyltransferase 5
  • Target synonyms
    60 kDa Tat-interactive protein; cPLA(2)-interacting protein; cPLA2; cPLA2 interacting protein; ESA1; histone acetyltransferase HTATIP; histone acetyltransferase KAT5; HIV-1 Tat interactive protein, 60kDa; HTATIP; HTATIP1; K(lysine) acetyltransferase 5; K-acetyltransferase 5; NEDFASB; PLIP; Tat interacting protein, 60kDa; TIP; TIP60; ZC2HC5
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ92993
  • Protein Name
    Histone acetyltransferase KAT5
  • Scientific Description
    The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
  • Reactivity
    Human, Mouse
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF. Chen Z et al., 2021 Oct 1, J Clin Invest
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  • Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. Wright DG et al., 2016 Jan 12, Oncotarget
    Read more
  • Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells. Collins HM et al., 2013 Jan 29, BMC Cancer
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