TIP60 antibody
GTX112198
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse
TargetKAT5
Overview
- SupplierGeneTex
- Product NameTIP60 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.67 mg/ml
- ConjugateUnconjugated
- Gene ID10524
- Target nameKAT5
- Target descriptionlysine acetyltransferase 5
- Target synonymsESA1, HTATIP, HTATIP1, NEDFASB, PLIP, TIP, TIP60, ZC2HC5, cPLA2, histone acetyltransferase KAT5, 60 kDa Tat-interactive protein, HIV-1 Tat interactive protein, 60kDa, K(lysine) acetyltransferase 5, K-acetyltransferase 5, Tat interacting protein, 60kDa, cPLA(2)-interacting protein, cPLA2 interacting protein, histone acetyltransferase HTATIP, protein 2-hydroxyisobutyryltransferase KAT5, protein acetyltransferase KAT5, protein crotonyltransferase KAT5, protein lactyltransferase KAT5
- HostRabbit
- IsotypeIgG
- Protein IDQ92993
- Protein NameHistone acetyltransferase KAT5
- Scientific DescriptionThe protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq]
- ReactivityHuman, Mouse
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Chen Z, Lu T, Huang L, et al. Circular RNA cia-MAF drives self-renewal and metastasis of liver tumor-initiating cells via transcription factor MAFF. J Clin Invest. 2021,131(19):pii: e148020. doi: 10.1172/JCI148020.Read this paper
- Wright DG, Marchal C, Hoang K, et al. Human T-cell leukemia virus type-1-encoded protein HBZ represses p53 function by inhibiting the acetyltransferase activity of p300/CBP and HBO1. Oncotarget. 2016,7(2):1687-706. doi: 10.18632/oncotarget.6424Read this paper
- Collins HM, Abdelghany MK, Messmer M, et al. Differential effects of garcinol and curcumin on histone and p53 modifications in tumour cells. BMC Cancer. 2013,13:37. doi: 10.1186/1471-2407-13-37Read this paper



![IHC-P analysis of human liver carcinoma (A), recturn carcinoma (B), normal medulla tissue (C) and normal interbrain tissue (D) using GTX83081 TIP60 antibody [3F9].](https://www.genetex.com/upload/website/prouct_img/normal/GTX83081/GTX83081_20170912_IHC-P_w_23061322_494.webp)

