Tipepidine [5169-78-8]

MedChem Express

Tipepidine [5169-78-8]

10

5169-78-8

Research Use Only

C15H17NS2

275.43

Tipepidine reversibly inhibits dopamine (DA) D2 receptor-mediated GIRK currents (IDA(GIRK)) with an IC50 of 7.0 microM. Tipepidine subsequently activates VTA dopamine neuron[1]. Tipepidine, a non-narcotic antitussive, exerts an antidepressant-like effect[2].

CN1C/C(CCC1)=C(C2=CC=CS2)\C3=CC=CS3

-20°C,2°C to 8°C

12352200