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Tirabrutinib

HY-15771
MedChem Express
CAS Number1351636-18-4
DownloadMSDS
Product group Chemicals
Estimated Purity99.71
Molecular Weight454.48
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Overview

  • Supplier
    MedChem Express
  • Product Name
    Tirabrutinib [1351636-18-4]
  • Delivery Days Customer
    10
  • CAS Number
    1351636-18-4
  • Certification
    Research Use Only
  • Estimated Purity
    99.71
  • Molecular Formula
    C25H22N6O3
  • Molecular Weight
    454.48
  • Scientific Description
    Tirabrutinib (ONO-4059) is an orally active Brutons Tyrosine Kinase (BTK) inhibitor (can cross the blood-brain barrier (BBB)), with an IC50 of 6.8 nM. Tirabrutinib irreversibly and covalently binds to BTK and inhibits aberrant B cell receptor signaling. Tirabrutinib can be used in studies of autoimmune diseases and hematological malignancies[1][2][3][4].
  • SMILES
    O=C1N(C2=CC=C(OC3=CC=CC=C3)C=C2)C4=C(N)N=CN=C4N1[C@H]5CN(C(C#CC)=O)CC5
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352200

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