TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF405S conjugate, 0.1mg/mL [26628-22-8]

Biotium

TLE1 (Synovial Sarcoma Marker) (TLE1/2085), CF405S conjugate, 0.1mg/mL [26628-22-8]

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

26628-22-8

Research Use Only

Monoclonal

TLE1/2085

0.1 mg/ml

Other Conjugate

TLE1

TLE family member 1, transcriptional corepressor

ESG, ESG1, GRG1, TLE-1, transducin-like enhancer protein 1, enhancer of split groucho-like protein 1, transducin like enhancer of split 1, transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)

Mouse

IgG2a

Transducin-like enhancer protein 1

Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Animal

Bovine, Human, Mouse

2°C to 8°C,RT

41116161