TLR2 antibody [TL2.1]

GeneTex

TLR2 antibody [TL2.1]

9

FACS: 1/10-1/50. Neutralizing/Inhibition: . *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Flow Cytometry, ImmunoPrecipitation, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, Neutralisation/Blocking

Research Use Only

Monoclonal

TL2.1

0.5 mg/ml

Unconjugated

TLR2

toll like receptor 2

CD282; TIL4; toll/interleukin-1 receptor-like protein 4; toll-like receptor 2

Mouse

IgG2a

Toll-like receptor 2

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the hosts inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

Canine, Human, Monkey, Primate

-20°C or -80°C,2°C to 8°C

12352203