TLR2 antibody

GTX21655

ApplicationsELISA, ImmunoHistoChemistry

DownloadDatasheet

Product group Antibodies

TargetTLR2

Overview

Supplier
GeneTex
Product Name
TLR2 antibody
Delivery Days Customer
9
Application Supplier Note
ELISA: 1:37,500. IHC: 1:125. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Concentration
1 mg/ml
Conjugate
Unconjugated
Gene ID7097
Target name
TLR2
Target description
toll like receptor 2
Target synonyms
CD282; TIL4; toll/interleukin-1 receptor-like protein 4; toll-like receptor 2
Host
Goat
Isotype
IgG
Protein IDO60603
Protein Name
Toll-like receptor 2
Scientific Description
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the hosts inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
Storage Instruction
-20°C or -80°C,2°C to 8°C
UNSPSC
12352203

References

An immunohistochemical study of Toll-like receptors 2 and 4 in placenta with and without infection. Hayati AR et al., 2010 Jun, Malays J Pathol
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References

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