Western blot analysis of extracts of various cell lines using TLR2 Polyclonal Antibody at dilution of 1:1000.
Western blot analysis of extracts of various cell lines using TLR2 Polyclonal Antibody at dilution of 1:1000.
TLR2 Polyclonal Antibody
E-AB-60720
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTLR2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. This protein is a cell-surface protein that can form heterodimers with other TLR family members to recognize conserved molecules derived from microorganisms known as pathogen-associated molecular patterns (PAMPs). Activation of TLRs by PAMPs leads to an up-regulation of signaling pathways to modulate the hosts inflammatory response. This gene is also thought to promote apoptosis in response to bacterial lipoproteins. This gene has been implicated in the pathogenesis of several autoimmune diseases. Alternative splicing results in multiple transcript variants.
- UNSPSC12352203