Human TLR4 detected by Western blot in transfected HEK293 cells (left lane)
Human TLR4 detected by Western blot in transfected HEK293 cells (left lane)
TLR4 antibody
GTX21436
ApplicationsFlow Cytometry, Western Blot
Product group Antibodies
ReactivityHuman
TargetTLR4
Overview
- SupplierGeneTex
- Product NameTLR4 antibody
- Delivery Days Customer9
- Application Supplier NoteFor WB: Use at a dilution of 1:2,700 - 1:3,300. The use of this product is also suitable for flow cytometry but not yet reported. Optimal dilutions/concentrations should be determined by the researcher.
- ApplicationsFlow Cytometry, Western Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7099
- Target nameTLR4
- Target descriptiontoll like receptor 4
- Target synonymsARMD10; CD284; homolog of Drosophila toll; hToll; TLR-4; TOLL; toll like receptor 4 protein; toll-like receptor 4
- HostRabbit
- IsotypeIgG
- Protein IDO00206
- Protein NameToll-like receptor 4
- Scientific DescriptionThe protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This receptor has been implicated in signal transduction events induced by lipopolysaccharide (LPS) found in most gram-negative bacteria. Mutations in this gene have been associated with differences in LPS responsiveness. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203