
Western blot analysis of extracts from HUVEC cells treated with PMA (125ng/ml, 30mins), and HUVEC cells treated with serum (20%, 30mins), using TNAP1 antibody.
TNFAIP1 Antibody
CSB-PA094566
ApplicationsWestern Blot, ELISA
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetTNFAIP1
Overview
- SupplierCusabio
- Product NameTNFAIP1 Antibody
- Delivery Days Customer20
- ApplicationsWestern Blot, ELISA
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7126
- Target nameTNFAIP1
- Target descriptionTNF alpha induced protein 1
- Target synonymsB12; B61; BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2; BTB/POZ domain-containing protein TNFAIP1; BTBD34; EDP1; hBACURD2; tumor necrosis factor, alpha induced protein 1; tumor necrosis factor, alpha-induced protein 1 (endothelial)
- HostRabbit
- IsotypeIgG
- Protein IDQ13829
- Protein NameBTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2
- Scientific DescriptionSubstrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis. May enhance the PCNA-dependent DNA polymerase delta activity. Wolf F.W., J. Biol. Chem. 267:1317-1326(1992). The MGC Project Team, Genome Res. 14:2121-2127(2004). Nousiainen M., Proc. Natl. Acad. Sci. U.S.A. 103:5391-5396(2006).
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C
- UNSPSC12352203