Western blot analysis of extracts of various cell lines using TNFRSF8 Polyclonal Antibody at dilution of 1:1000.
TNFRSF8 Polyclonal Antibody
E-AB-62031
Product group Antibodies
Overview
- SupplierElabscience
- Product NameTNFRSF8 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThe protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
- UNSPSC12352203