
Immunohistochemistry of paraffin-embedded human appendix tissue using CSB-PA023998LA01HU at dilution of 1:100
TNIK Antibody
CSB-PA023998LA01HU
ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTNIK
Overview
- SupplierCusabio
- Product NameTNIK Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID23043
- Target nameTNIK
- Target descriptionTRAF2 and NCK interacting kinase
- Target synonymsMRT54; TRAF2 and NCK-interacting protein kinase
- HostRabbit
- IsotypeIgG
- Protein IDQ9UKE5
- Protein NameTRAF2 and NCK-interacting protein kinase
- Scientific DescriptionSerine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203