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Tolebrutinib [1971920-73-6]

Tolebrutinib [1971920-73-6]

T9125
TargetMol Chemicals
CAS Number1971920-73-6
DownloadMSDS
Product group Chemicals
Estimated Purity0.99
Molecular Weight455.51
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Tolebrutinib [1971920-73-6]
  • Delivery Days Customer
    9
  • CAS Number
    1971920-73-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Tolebrutinib
  • Estimated Purity
    0.99
  • Molecular Formula
    C26H25N5O3
  • Molecular Weight
    455.51
  • Scientific Description
    Tolebrutinib (PRN2246) is a potent, selective, orally active and brain-penetrant Bruton tyrosine kinase (BTK) inhibitor(IC50s of 0.4 and 0.7 nM in Ramos B cells and in HMC microglia cells, respectively). It exhibits efficacy in central nervous system immunity. Tolebrutinib can be used for the research of multiple sclerosis (MS).
  • Shelf life instruction
    3 years
  • SMILES
    Nc1nccc2n([C@@H]3CCCN(C3)C(=O)C=C)c(=O)n(-c3ccc(Oc4ccccc4)cc3)c12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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