Tollip antibody [N2C3]
GTX116566
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTOLLIP
Overview
- SupplierGeneTex
- Product NameTollip antibody [N2C3]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.63 mg/ml
- ConjugateUnconjugated
- Gene ID54472
- Target nameTOLLIP
- Target descriptiontoll interacting protein
- Target synonymsadapter protein; IL-1RAcPIP; toll-interacting protein
- HostRabbit
- IsotypeIgG
- Protein IDQ9H0E2
- Protein NameToll-interacting protein
- Scientific DescriptionThis gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. [supplied by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesicles. Ryan TA et al., 2020 Jun 2, EMBO JRead more
- Fucose-containing fraction of Ling-Zhi enhances lipid rafts-dependent ubiquitination of TGFbeta receptor degradation and attenuates breast cancer tumorigenesis. Tsao SM et al., 2016 Nov 10, Sci RepRead more
- Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament binding. Arden SD et al., 2016 Oct 1, Biochem JRead more