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Tollip antibody [N2C3]

Research Use Only
GTX116566
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTOLLIP
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Overview

  • Supplier
    GeneTex
  • Product Name
    Tollip antibody [N2C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.63 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID54472
  • Target name
    TOLLIP
  • Target description
    toll interacting protein
  • Target synonyms
    adapter protein; IL-1RAcPIP; toll-interacting protein
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9H0E2
  • Protein Name
    Toll-interacting protein
  • Scientific Description
    This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. [supplied by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Tollip coordinates Parkin-dependent trafficking of mitochondrial-derived vesicles. Ryan TA et al., 2020 Jun 2, EMBO J
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  • Fucose-containing fraction of Ling-Zhi enhances lipid rafts-dependent ubiquitination of TGFbeta receptor degradation and attenuates breast cancer tumorigenesis. Tsao SM et al., 2016 Nov 10, Sci Rep
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  • Loss of cargo binding in the human myosin VI deafness mutant (R1166X) leads to increased actin filament binding. Arden SD et al., 2016 Oct 1, Biochem J
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