Torin 2 [1223001-51-1]
S2817
CAS Number1223001-51-1
Product group Chemicals
Overview
- SupplierSelleck Chemicals
- Product NameTorin 2 [1223001-51-1]
- Delivery Days Customer9
- CAS Number1223001-51-1
- CertificationResearch Use Only
- Scientific DescriptionTorin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53−/− MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM,in PC3 cell lines respectively. Torin 2 decreases cell viability and induces autophagy and apoptosis.
- UNSPSC12352200
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