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Torin 2 [1223001-51-1]

Research Use Only
S2817
Selleck Chemicals
CAS Number1223001-51-1
Product group Chemicals
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Overview

  • Supplier
    Selleck Chemicals
  • Product Name
    Torin 2 [1223001-51-1]
  • Delivery Days Customer
    9
  • CAS Number
    1223001-51-1
  • Certification
    Research Use Only
  • Scientific Description
    Torin 2 is a potent and selective mTOR inhibitor with IC50 of 0.25 nM in p53−/− MEFs cell line; 800-fold greater selectivity for mTOR than PI3K and improved pharmacokinetic properties. Inhibition of ATM/ATR/DNA-PK with EC50 of 28 nM/35 nM/118 nM,in PC3 cell lines respectively. Torin 2 decreases cell viability and induces autophagy and apoptosis.
  • UNSPSC
    12352200

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