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TP0427736 hydrochloride [2459963-17-6]
T61029
Overview
- SupplierTargetMol Chemicals
- Product NameTP0427736 hydrochloride [2459963-17-6]
- Delivery Days Customer14
- CAS Number2459963-17-6
- Category SupplierChemical
- CertificationResearch Use Only
- Chemical NameTP0427736 hydrochloride
- Molecular FormulaC14H11ClN4S2
- Molecular Weight334.84
- Scientific DescriptionTP0427736 hydrochloride can be used in the androgenic alopecia (AGA) research. TP0427736 hydrochloride inhibits the phosphorylation of Smad2/3 in A549 cells induced by TGF-beta1 with an IC50 value of 8.68 nM. TP0427736 hydrochloride is a potent ALK5 kinase inhibitor with an IC50 value of 2.72 nM which is 300-fold more potent than inhibitory effect against ALK3 of 836 nM [1].
- Shelf life instruction3 years
- SMILESCl.Cc1csc(n1)-c1nc[nH]c1-c1ccc2ncsc2c1
- Storage Instruction-20°C
- UNSPSC12352200