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TP0427736 hydrochloride [2459963-17-6]

TP0427736 hydrochloride [2459963-17-6]

T61029
TargetMol Chemicals
CAS Number2459963-17-6
Product group Chemicals
Molecular Weight334.84
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    TP0427736 hydrochloride [2459963-17-6]
  • Delivery Days Customer
    14
  • CAS Number
    2459963-17-6
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    TP0427736 hydrochloride
  • Molecular Formula
    C14H11ClN4S2
  • Molecular Weight
    334.84
  • Scientific Description
    TP0427736 hydrochloride can be used in the androgenic alopecia (AGA) research. TP0427736 hydrochloride inhibits the phosphorylation of Smad2/3 in A549 cells induced by TGF-beta1 with an IC50 value of 8.68 nM. TP0427736 hydrochloride is a potent ALK5 kinase inhibitor with an IC50 value of 2.72 nM which is 300-fold more potent than inhibitory effect against ALK3 of 836 nM [1].
  • Shelf life instruction
    3 years
  • SMILES
    Cl.Cc1csc(n1)-c1nc[nH]c1-c1ccc2ncsc2c1
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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