tPA antibody detects PLAT protein by western blot analysis. A. 30 μg Neuro2A whole cell lysate/extract 7.5% SDS-PAGE tPA antibody (GTX103453) dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
tPA antibody detects PLAT protein by western blot analysis. A. 30 μg Neuro2A whole cell lysate/extract 7.5% SDS-PAGE tPA antibody (GTX103453) dilution: 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.
tPA antibody
GTX103453
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetPLAT
Overview
- SupplierGeneTex
- Product NametPA antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.15 mg/ml
- ConjugateUnconjugated
- Gene ID5327
- Target namePLAT
- Target descriptionplasminogen activator, tissue type
- Target synonymsT-PA, TPA, tissue-type plasminogen activator, alteplase, plasminogen/activator kringle, reteplase, t-plasminogen activator
- HostRabbit
- IsotypeIgG
- Protein IDP00750
- Protein NameTissue-type plasminogen activator
- Scientific DescriptionThis gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Svalina MN, Kikuchi K, Abraham J, et al. IGF1R as a Key Target in High Risk, Metastatic Medulloblastoma. Sci Rep. 2016,6:27012. doi: 10.1038/srep27012Read this paper
Datasheet
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