tPA antibody

GeneTex

tPA antibody

9

WB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.15 mg/ml

Unconjugated

PLAT

plasminogen activator, tissue type

alteplase; plasminogen/activator kringle; reteplase; tissue-type plasminogen activator; TPA; T-PA; t-plasminogen activator

Rabbit

IgG

Tissue-type plasminogen activator

This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding; decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203