ICC/IF analysis of U87-MG cells using GTX57582 TPMT antibody. Blue: DAPI Green: Primary antibody Dilution: 1:100
ICC/IF analysis of U87-MG cells using GTX57582 TPMT antibody. Blue: DAPI Green: Primary antibody Dilution: 1:100
TPMT antibody [AT2E7]
GTX57582
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
ReactivityHuman
TargetTPMT
Overview
- SupplierGeneTex
- Product NameTPMT antibody [AT2E7]
- Delivery Days Customer9
- Application Supplier NoteWB: 1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDAT2E7
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID7172
- Target nameTPMT
- Target descriptionthiopurine S-methyltransferase
- Target synonymsS-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine S-methyltransferase; TPMTD
- HostMouse
- IsotypeIgG1
- Protein IDP51580
- Protein NameThiopurine S-methyltransferase
- Scientific DescriptionThis gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203