WB analysis of K562 cell lysate using GTX16383 TPMT antibody. Dilution : 1:1000 Loading : 25microg per lane
WB analysis of K562 cell lysate using GTX16383 TPMT antibody. Dilution : 1:1000 Loading : 25microg per lane
TPMT antibody
GTX16383
Overview
- SupplierGeneTex
- Product NameTPMT antibody
- Delivery Days Customer7
- Application Supplier NoteWB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- Gene ID7172
- Target nameTPMT
- Target descriptionthiopurine S-methyltransferase
- Target synonymsS-adenosyl-L-methionine:thiopurine S-methyltransferase; thiopurine S-methyltransferase; TPMTD
- HostRabbit
- IsotypeIgG
- Protein IDP51580
- Protein NameThiopurine S-methyltransferase
- Scientific DescriptionThis gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203