TPX2 Polyclonal Antibody

Reddot Biotech

TPX2 Polyclonal Antibody

5

Western Blot, ELISA

Research Use Only

Polyclonal

0.9 mg/ml

Unconjugated

TPX2

TPX2 microtubule nucleation factor

C20orf1; C20orf2; differentially expressed in cancerous and non-cancerous lung cells 2; differentially expressed in lung cells; DIL2; DIL-2; FLS353; GD:C20orf1; HCA519; HCTP4; hepatocellular carcinoma-associated antigen 519; hepatocellular carcinoma-associated antigen 90; p100; preferentially expressed in colorectal cancer; protein fls353; REPP86; restricted expression proliferation associated protein 100; targeting protein for Xklp2; TPX2, microtubule-associated protein homolog; TPX2, microtubule-associated, homolog

Rabbit

IgG

TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.

Human, Mouse

-20°C

12352203