Trap1 Antibody (OASE00139)

Aviva Systems Biology

Trap1 Antibody (OASE00139)

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

Trap1-6

1 mg/ml

Unconjugated

TRAP1

TNF receptor associated protein 1

HSP 75, HSP75, HSP90L, TRAP-1, heat shock protein 75 kDa, mitochondrial, TNFR-associated protein 1, heat shock protein family C member 5, testicular tissue protein Li 209, tumor necrosis factor type 1 receptor-associated protein

Mouse

IgG2a

The 90 kDa heat shock protein (HSP90) family of proteins that play an important physiological role. HSP90 is involved in numerous cellular processes but is best known for its association with signal transduction machinery. A recently cloned homolog of HSP90 is the tumor necrosis factor receptor-associated protein (TRAP1). Like HSP90, TRAP1 is found to be associated with numerous proteins involved in diverse actions (1, 2). Immunofluorescence data has shown TRAP1 to be localized in the mitochondria of mammalian cells. This observation and the fact that TRAP1 is shown to have a mitochondrial targeting pre-sequence strongly implicates TRAP1 as a mitochondrial matrix protein (3).

-20°C

12352203