Bio-Connect

TRAP80 antibody [C1C3]

GTX115241
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetMED17
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Overview

  • Supplier
    GeneTex
  • Product Name
    TRAP80 antibody [C1C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID9440
  • Target name
    MED17
  • Target description
    mediator complex subunit 17
  • Target synonyms
    activator-recruited cofactor 77 kDa component; ARC77; cofactor required for Sp1 transcriptional activation, subunit 6, 77kDa; CRSP complex subunit 6; CRSP6; CRSP77; DRIP80; epididymis secretory sperm binding protein; mediator of RNA polymerase II transcription subunit 17; SRB4; thyroid hormone receptor-associated protein complex 80 kDa component; transcriptional coactivator CRSP77; TRAP80; vitamin D3 receptor-interacting protein complex 80 kDa component
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ9NVC6
  • Protein Name
    Mediator of RNA polymerase II transcription subunit 17
  • Scientific Description
    The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Distinct roles for CKM-Mediator in controlling Polycomb-dependent chromosomal interactions and priming genes for induction.
    Read more
  • Regulated splicing of large exons is linked to phase-separation of vertebrate transcription factors.
    Read more