TRC8 antibody, C-term

GeneTex

TRC8 antibody, C-term

9

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

0.50 mg/ml

Unconjugated

RNF139

ring finger protein 139

E3 ubiquitin-protein ligase RNF139; HRCA1; multiple membrane spanning receptor TRC8; patched related protein translocated in renal cancer; RCA1; RING-type E3 ubiquitin transferase RNF139; translocation in renal carcinoma on chromosome 8 protein; translocation in renal carcinoma, chromosome 8; TRC8

Goat

IgG

E3 ubiquitin-protein ligase RNF139

The protein encoded by this gene is a multi-membrane spanning protein containing a RING-H2 finger. This protein is located in the endoplasmic reticulum, and has been shown to possess ubiquitin ligase activity. This gene was found to be interrupted by a t(3:8) translocation in a family with hereditary renal and non-medulary thyroid cancer. Studies of the Drosophila counterpart suggested that this protein may interact with tumor suppressor protein VHL, as well as with COPS5/JAB1, a protein responsible for the degradation of tumor suppressor CDKN1B/P27KIP. [provided by RefSeq, Jul 2008]

-20°C or -80°C,2°C to 8°C

12352203