Western Blot Positive WB detected in: MCF-7 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate, K562 whole cell lysate All lanes: TRIM25 antibody at 3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 71 kDa Observed band size: 71, 80 kDa
Western Blot Positive WB detected in: MCF-7 whole cell lysate, Jurkat whole cell lysate, Hela whole cell lysate, K562 whole cell lysate All lanes: TRIM25 antibody at 3ug/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 71 kDa Observed band size: 71, 80 kDa
TRIM25 Antibody
CSB-PA617909LA01HU
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetTRIM25
Overview
- SupplierCusabio
- Product NameTRIM25 Antibody
- Delivery Days Customer20
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7706
- Target nameTRIM25
- Target descriptiontripartite motif containing 25
- Target synonymsE3 ubiquitin/ISG15 ligase TRIM25; EFP; estrogen-responsive finger protein; RING finger protein 147; RING-type E3 ubiquitin transferase TRIM25; RNF147; tripartite motif protein TRIM25; tripartite motif-containing protein 25; ubiquitin/ISG15-conjugating enzyme TRIM25; Z147; zinc finger protein 147 (estrogen-responsive finger protein); zinc finger protein-147; ZNF147
- HostRabbit
- IsotypeIgG
- Protein IDQ14258
- Protein NameE3 ubiquitin/ISG15 ligase TRIM25
- Scientific DescriptionFunctions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates \\\Lys-63\\\-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).
- ReactivityHuman
- Storage Instruction-20°C or -80°C
- UNSPSC12352203