TRIM25 antibody
![Research Use Only](static/images/certificates/ruo.jpg)
GTX116209
ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTRIM25
Overview
- SupplierGeneTex
- Product NameTRIM25 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- FormulationLiquid
- Gene ID7706
- Target nameTRIM25
- Target descriptiontripartite motif containing 25
- Target synonymsE3 ubiquitin/ISG15 ligase TRIM25; EFP; estrogen-responsive finger protein; RING finger protein 147; RING-type E3 ubiquitin transferase TRIM25; RNF147; tripartite motif protein TRIM25; tripartite motif-containing protein 25; ubiquitin/ISG15-conjugating enzyme TRIM25; Z147; zinc finger protein 147 (estrogen-responsive finger protein); zinc finger protein-147; ZNF147
- HostRabbit
- IsotypeIgG
- Protein IDQ14258
- Protein NameE3 ubiquitin/ISG15 ligase TRIM25
- Scientific DescriptionThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to the cytoplasm. The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor, similar to several other members of the TRIM family. Expression of the gene is upregulated in response to estrogen, and it is thought to mediate estrogen actions in breast cancer as a primary response gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Expression of Zinc-Finger Antiviral Protein in hCMEC/D3 Human Cerebral Microvascular Endothelial Cells: Effect of a Toll-Like Receptor 3 Agonist. Okudera M et al., 2021 Dec 22, NeuroimmunomodulationRead more
- Cross-talk between SUMOylation and ISGylation in response to interferon. El-Asmi F et al., 2020 May, CytokineRead more
- TRIM25 is associated with cisplatin resistance in non-small-cell lung carcinoma A549 cell line via downregulation of 14-3-3sigma. Qin X et al., 2017 Nov 4, Biochem Biophys Res CommunRead more