TrpC7 Antibody (OASE00191)

Aviva Systems Biology

TrpC7 Antibody (OASE00191)

23

ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, Other Application

Research Use Only

Monoclonal

S64A-36

1 mg/ml

Unconjugated

TRPC7

transient receptor potential cation channel subfamily C member 7

likley ortholog of mouse transient receptor potential cation channel, subfamily C, member 7; putative capacitative calcium channel; short transient receptor potential channel 7; transient receptor protein 7; TRP7

Mouse

IgG1

Transient receptor potential cation channel, subfamily C, member 7, also known as TRPC7, is a non-selective cation channel that is directly activated by DAG. TrpC7 shows constitutive activity and susceptibility to negative regulation by extracellular Ca2+. Because of this, TrpC7 plays an important role in the Ca2+ signaling pathway (1). TrpC7 is also expressed abundantly in the heart, and combined with its ability to act as a Ca2+ channel, TrpC7 might contribute to the process of heart failure (2).

Human, Mouse, Rat

-20°C

12352203