TrxR1 antibody [N3C2], Internal

GeneTex

TrxR1 antibody [N3C2], Internal

9

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

TXNRD1

thioredoxin reductase 1

GRIM-12, TR, TR1, TRXR1, TXNR, TXNR1, thioredoxin reductase 1, cytoplasmic, KM-102-derived reductase-like factor, gene associated with retinoic and IFN-induced mortality 12 protein, gene associated with retinoic and interferon-induced mortality 12 protein, oxidoreductase, peroxidase TXNRD1, selenoprotein TXNRD1, testis tissue sperm-binding protein Li 46a, thioredoxin reductase GRIM-12, thioredoxin reductase TR1

Rabbit

IgG

Thioredoxin reductase 1, cytoplasmic

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3 UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq]

Human, Mouse, Rat

-20°C or -80°C,2°C to 8°C

12352203