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Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TTI1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TTI1 Polyclonal Antibody at dilution 1:40
Immunohistochemistry of paraffin-embedded Human prostate cancer tissue using TTI1 Polyclonal Antibody at dilution 1:40

TTI1 Polyclonal Antibody

Research Use Only
E-AB-17482
Elabscience
Product group Antibodies
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Overview

  • Supplier
    Elabscience
  • Product Name
    TTI1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    Regulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
  • UNSPSC
    12352203