TTI1 Polyclonal Antibody
RD79748A
ApplicationsELISA, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman, Mouse
TargetTTI1
Overview
- SupplierReddot Biotech
- Product NameTTI1 Polyclonal Antibody
- Delivery Days Customer5
- ApplicationsELISA, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1.2 mg/ml
- ConjugateUnconjugated
- Gene ID9675
- Target nameTTI1
- Target descriptionTELO2 interacting protein 1
- Target synonymsKIAA0406; smg-10; smg-10 homolog, nonsense mediated mRNA decay factor; Tel two interacting protein 1; TEL2-interacting protein 1 homolog; TELO2-interacting protein 1 homolog
- HostRabbit
- IsotypeIgG
- Scientific DescriptionRegulator of the DNA damage response (DDR). Part of the TTT complex that is required to stabilize protein levels of the phosphatidylinositol 3-kinase-related protein kinase (PIKK) family proteins. The TTT complex is involved in the cellular resistance to DNA damage stresses, like ionizing radiation (IR), ultraviolet (UV) and mitomycin C (MMC). Together with the TTT complex and HSP90 may participate in the proper folding of newly synthesized PIKKs. Promotes assembly, stabilizes and maintains the activity of mTORC1 and mTORC2 complexes, which regulate cell growth and survival in response to nutrient and hormonal signals.
- ReactivityHuman, Mouse
- Storage Instruction-20°C
- UNSPSC12352203