Tucidinostat

MedChem Express

Tucidinostat [1616493-44-7]

10

1616493-44-7

Research Use Only

98.60

C22H19FN4O2

390.41

Tucidinostat (Chidamide) is a potent and orally bioavailable HDAC enzymes class I ( HDAC1/2/3 ) and class IIb ( HDAC10 ) inhibitor, with IC 50 s of 95, 160, 67 and 78 nM, less active on HDAC8 and HDAC11 ( IC 50 s, 733 nM, 432 nM, respectively), and shows no effect on HDAC4/5/6/7/9 [1] .

O=C(C1=CC=C(CNC(/C=C/C2=CN=CC=C2)=O)C=C1)NC(C=CC(F)=C3)=C3N

-20°C,2°C to 8°C

12352200