Tucidinostat (Chidamide)

AbMole BioScience

Tucidinostat (Chidamide)

9

1616493-44-7

Chemical

Research Use Only

C22H19FN4O2

390.41

Tucidinostat (Chidamide) is a low nanomolar inhibitor of HDAC1, 2, 3, and 10, the HDAC isotypes well documented to be associated with the malignant phenotype with IC50 values of 95, 160, 67, 78 nM for HDAC1, 2, 3, 10 respectively.

NC1=C(NC(=O)C2=CC=C(CNC(=O)\C=C\C3=CC=CN=C3)C=C2)C=C(F)C=C1

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