TX1-85-1

Biorbyt

TX1-85-1 [1603845-32-4]

10

1603845-32-4

Research Use Only

C32H36N8O3

580.693

TX1-85-1 is a potent, selective, ATP-competitive Her3 (ErbB3) inhibitor with IC50 of 23 nM, forms a covalent bond with Cys721 located in the ATP-binding site of Her3.

C(NC1=CC(C2C3=C(N)N=CN=C3N(C3CCC(N4CCN(C(C)=O)CC4)CC3)N=2)=CC=C1OC1=CC=CC=C1)(=O)C=C

12352200