TXNDC5 antibody
GTX106914
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTXNDC5
Overview
- SupplierGeneTex
- Product NameTXNDC5 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID81567
- Target nameTXNDC5
- Target descriptionthioredoxin domain containing 5
- Target synonymsENDOPDI; endoplasmic reticulum protein ERp46; endoplasmic reticulum resident protein 46; endothelial protein disulphide isomerase; epididymis secretory sperm binding protein; ER protein 46; ERP46; HCC2; HCC-2; PDIA15; protein disulfide isomerase family A, member 15; STRF8; thioredoxin domain containing 5 (endoplasmic reticulum); thioredoxin domain-containing protein 5; thioredoxin related protein; thioredoxin-like protein p46; UNQ364
- HostRabbit
- IsotypeIgG
- Protein IDQ8NBS9
- Protein NameThioredoxin domain-containing protein 5
- Scientific DescriptionThis gene encodes a protein-disulfide isomerase. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Redox states in the endoplasmic reticulum directly regulate the activity of calcium channel, inositol 1,4,5-trisphosphate receptors.Read more
- Inhibition of NR4A1 Promotes ROS Accumulation and IL24-Dependent Growth Arrest in Rhabdomyosarcoma. Hedrick E et al., 2019 Nov, Mol Cancer ResRead more
- Nuclear receptor 4A1 as a drug target for breast cancer chemotherapy. Hedrick E et al., 2015 Oct, Endocr Relat CancerRead more
- The orphan nuclear receptor NR4A1 (Nur77) regulates oxidative and endoplasmic reticulum stress in pancreatic cancer cells. Lee SO et al., 2014 Apr, Mol Cancer ResRead more