The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using CSB-PA296101(TXNIP Antibody) at dilution 1/40, on the right is treated with synthetic peptide. (Original magnification: x200)

TXNIP Antibody

Name: TXNIP Antibody
SKU: CSB-PA296101_C90
Availability: BackOrder

CSB-PA296101

ApplicationsELISA, ImmunoHistoChemistry

Product group Antibodies

ReactivityHuman, Mouse, Rat

TargetTXNIP

Overview

Supplier
Cusabio
Product Name
TXNIP Antibody
Delivery Days Customer
20
Applications
ELISA, ImmunoHistoChemistry
Certification
Research Use Only
Clonality
Polyclonal
Conjugate
Unconjugated
Gene ID10628
Target name
TXNIP
Target description
thioredoxin interacting protein
Target synonyms
ARRDC6, EST01027, HHCPA78, THIF, VDUP1, thioredoxin-interacting protein, thioredoxin binding protein 2, upregulated by 1,25-dihydroxyvitamin D-3, vitamin D3 up-regulated protein 1
Host
Rabbit
Isotype
IgG
Protein IDQ9H3M7
Protein Name
Thioredoxin-interacting protein
Scientific Description
May act as an oxidative stress mediator by inhibiting thioredoxin activity or by limiting its bioavailability. Interacts with COPS5 and restores COPS5-induced suppression of CDKN1B stability, blocking the COPS5-mediated translocation of CDKN1B from the nucleus to the cytoplasm. Functions as a transcriptional repressor, possibly by acting as a bridge molecule between transcription factors and corepressor complexes, and over-expression will induce G0/G1 cell cycle arrest. Required for the maturation of natural killer cells. Acts as a suppressor of tumor cell growth. Inhibits the proteasomal degradation of DDIT4, and thereby contributes to the inhibition of the mammalian target of rapamycin complex 1 (mTORC1).
Reactivity
Human, Mouse, Rat
Storage Instruction
-20°C or -80°C
UNSPSC
41116161

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TXNIP Antibody

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