TYK2 antibody

GeneTex

TYK2 antibody

9

At least three isoforms of TYK2 are known to exist; this antibody only detects the two longest isoforms.

WB: 1 - 2 microg/mL. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

TYK2

tyrosine kinase 2

IMD35; JTK1; non-receptor tyrosine-protein kinase TYK2

Rabbit

IgG

Non-receptor tyrosine-protein kinase TYK2

This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq, Jul 2008]

Human, Mouse, Rat

2°C to 8°C

12352203